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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304849
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atad2
Name: ATPase family, AAA domain containing 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atad2decreases expressionISOATAD2 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ATAD2 mRNAPMID:20064835 PMID:20106945 PMID:21632981 PMID:21802500
Atad2decreases expressionISOAtad2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ATAD2 mRNAPMID:19770486
Atad2increases expressionISOAtad2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of ATAD2 mRNAPMID:20713471
Atad2multiple interactionsISOAtad2 (Mus musculus)6480464CTD[Benzo(a)pyrene results in increased activity of AHR protein] which results in decreased expression of ATAD2 mRNAPMID:32553695
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