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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304566
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igsf9
Name: immunoglobulin superfamily, member 9
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igsf9affects methylationISOIGSF9 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of IGSF9 3' UTR; Benzo(a)pyrene affects the methylation of IGSF9 5' UTR; Benzo(a)pyrene affects the methylation of IGSF9 intronPMID:27901495 PMID:30157460
Igsf9decreases expressionISOIGSF9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of IGSF9 mRNAPMID:32234424
Igsf9decreases methylationISOIGSF9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of IGSF9 promoterPMID:27901495
Igsf9increases expressionISOIgsf9 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of IGSF9 mRNAPMID:22228805 PMID:23735875
Igsf9multiple interactionsISOIgsf9 (Mus musculus)6480464CTDAHR protein affects the reaction [Benzo(a)pyrene affects the expression of IGSF9 mRNA]PMID:22228805
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