GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kcne4 | affects methylation | ISO | KCNE4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of KCNE4 exon; Benzo(a)pyrene affects the methylation of KCNE4 promoter | PMID:27901495 | Kcne4 | increases expression | ISO | Kcne4 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of KCNE4 mRNA | PMID:22228805 PMID:27195522 | Kcne4 | multiple interactions | ISO | Kcne4 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [AHR protein binds to KCNE4 promoter] | PMID:19654925 | |
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