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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:29852
Term: methylarsonic acid
Definition: An arsonic acid that has formula CH5AsO3.
Chemical ID: MESH:C020300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDmonomethylarsonic acid results in decreased expression of HMOX1 mRNA

PMID:24091636
increases expressionISORGD:107176480464CTDmonomethylarsonic acid results in increased expression of HMOX1 mRNA

PMID:15345372
increases expressionISORGD:7309016480464CTDmonomethylarsonic acid results in increased expression of HMOX1 mRNA

PMID:24091636
multiple interactionsISORGD:7309016480464CTD[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of HMOX1 mRNA

PMID:23192986
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.