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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319562
Species: Mus musculus
RGD Object: Gene
Symbol: Spry1
Name: sprouty RTK signaling antagonist 1
Acc ID: CHEBI:2979
Term: baicalein
Definition: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
Chemical ID: MESH:C006680
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spry1multiple interactionsISOSPRY1 (Homo sapiens)6480464CTDbaicalein inhibits the reaction [TGFB1 protein results in decreased expression of SPRY1 protein]; SPRY1 protein affects the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]PMID:30201452
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