GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fgf21 | increases expression | ISO | Fgf21 (Mus musculus) | 6480464 | CTD | Tunicamycin results in increased expression of FGF21 mRNA; Tunicamycin results in increased expression of FGF21 protein | PMID:23123503 | Fgf21 | multiple interactions | ISO | FGF21 (Homo sapiens) | 6480464 | CTD | FGF21 protein inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]; FGF21 protein inhibits the reaction [Tunicamycin results in increased expression of VLDLR mRNA]; FGF21 protein inhibits the reaction [Tunicamycin results in increased expression of VLDLR protein]; FGF21 protein inhibits the reaction [Tunicamycin results in increased phosphorylation of EIF2S1 protein] | PMID:29289645 | Fgf21 | multiple interactions | ISO | Fgf21 (Mus musculus) | 6480464 | CTD | FGF21 protein inhibits the reaction [Tunicamycin promotes the reaction [PPARD gene mutant form results in increased expression of VLDLR mRNA]]; FGF21 protein inhibits the reaction [Tunicamycin promotes the reaction [PPARD gene mutant form results in increased uptake of Triglycerides]]; FGF21 protein inhibits the reaction [Tunicamycin results in increased expression of VLDLR mRNA]; FGF21 protein inhibits the reaction [Tunicamycin results in increased expression of VLDLR protein]; Tunicamycin inhibits the reaction [FGF21 protein inhibits the reaction [PPARD gene mutant form results in increased uptake of Triglycerides]] | PMID:29289645 | | ||||||||||||||||||||||
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