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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:29681
Term: surfactin
Definition: Any mixture comprising isoforms of a bacterial cyclic lipopeptide antibiotic produced by various strains of Bacillus subtilis. The isoforms are cyclodepsipeptides containing at least seven amino acid residues. Among the most effective biosurfactants, surfactin can reduce the surface tension of water from 72 to 27 mN/m at a concentration as low as 0.005%.
Chemical ID: MESH:C009365
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTDsurfactin peptide results in increased phosphorylation of MAPK9 proteinPMID:34850538
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTD4-methylumbelliferone 8-carbaldehyde inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK9 protein]; KIRA6 inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK9 protein]PMID:34850538
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