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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559716
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ern1
Name: endoplasmic reticulum to nucleus signaling 1
Acc ID: CHEBI:29681
Term: surfactin
Definition: Any mixture comprising isoforms of a bacterial cyclic lipopeptide antibiotic produced by various strains of Bacillus subtilis. The isoforms are cyclodepsipeptides containing at least seven amino acid residues. Among the most effective biosurfactants, surfactin can reduce the surface tension of water from 72 to 27 mN/m at a concentration as low as 0.005%.
Chemical ID: MESH:C009365
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ern1increases phosphorylationISOERN1 (Homo sapiens)6480464CTDsurfactin peptide results in increased phosphorylation of ERN1 proteinPMID:34850538
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