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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736723
Species: Homo sapiens
RGD Object: Gene
Symbol: NEFH
Name: neurofilament heavy chain
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NEFHdecreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of NEFH mRNAPMID:19615344
NEFHmultiple interactionsEXP 6480464CTDmonoisoamyl-2,3-dimercaptosuccinate inhibits the reaction [sodium arsenite results in decreased expression of NEFH mRNA]PMID:19615344
NEFHdecreases phosphorylationISONefh (Rattus norvegicus)6480464CTDsodium arsenite results in decreased phosphorylation of NEFH proteinPMID:18674524
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