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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736625
Species: Homo sapiens
RGD Object: Gene
Symbol: PRPS1
Name: phosphoribosyl pyrophosphate synthetase 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRPS1affects expressionEXP 6480464CTDsodium arsenite affects the expression of PRPS1 mRNAPMID:34032870
PRPS1increases expressionEXP 6480464CTDsodium arsenite results in increased expression of PRPS1 mRNAPMID:28595984
PRPS1decreases expressionISOPrps1 (Rattus norvegicus)6480464CTDsodium arsenite results in decreased expression of PRPS1 proteinPMID:29459688
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