Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736024
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9affects expressionEXP 6480464CTDsodium arsenite affects the expression of MAPK9PMID:25367288
Mapk9increases expressionEXP 6480464CTDsodium arsenite results in increased expression of MAPK9 protein modified formPMID:28757890
Mapk9increases phosphorylationEXP 6480464CTDsodium arsenite results in increased phosphorylation of MAPK9 proteinPMID:16973625 PMID:18996350 PMID:28843991 PMID:34272803
Mapk9multiple interactionsEXP 6480464CTDCDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK9 protein modified form]; MAPK9 protein affects the reaction [sodium arsenite results in increased expression of HSPA1A protein]; MAPK9 protein affects the reaction [sodium arsenite results in increased expression of HSPB1 protein]; MAPK9 protein affects the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of HSF1 protein]; MAPK9 protein promotes the reaction [sodium arsenite results in increased activity of CASP3 protein]; MAPK9 protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; MAPK9 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A mRNA]; MAPK9 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A protein]; MAPK9 protein promotes the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of JUN protein]; sodium arsenite results in increased phosphorylation of and results in increased activity of MAPK9 proteinPMID:16973625 PMID:20566634 PMID:23143138 PMID:28757890 PMID:34272803
Mapk9increases activityISOMapk9 (Rattus norvegicus)6480464CTDsodium arsenite results in increased activity of MAPK9 proteinPMID:17658681
Mapk9increases activityISOMAPK9 (Homo sapiens)6480464CTDsodium arsenite results in increased activity of MAPK9 proteinPMID:22706169
Mapk9increases expressionISOMapk9 (Rattus norvegicus)6480464CTDsodium arsenite results in increased expression of MAPK9 proteinPMID:27966075
Mapk9increases phosphorylationISOMapk9 (Rattus norvegicus)6480464CTDsodium arsenite results in increased phosphorylation of MAPK9 proteinPMID:11408547 PMID:21621526 PMID:24952339
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTDsodium arsenite results in increased phosphorylation of MAPK9 proteinPMID:12482858 PMID:19154403 PMID:21642427 PMID:24184208 PMID:26404762
Mapk9multiple interactionsISOMapk9 (Rattus norvegicus)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK9 protein]; [Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK9 protein; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [sodium arsenite results in increased activity of MAPK9 protein]; Vinyl Compounds analog inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]PMID:17658681 PMID:20829427 PMID:21621526 PMID:24952339 PMID:27966075
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTD[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNA; sodium arsenite promotes the reaction [MAPK8 protein binds to MAPK9 protein binds to TP53 protein modified form]; tetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]PMID:12634122 PMID:22706169 PMID:26404762
Go Back to source page   Continue to Ontology report