Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734069
Species: Homo sapiens
RGD Object: Gene
Symbol: ID3
Name: inhibitor of DNA binding 3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ID3decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of ID3 mRNAPMID:12727804
ID3increases expressionEXP 6480464CTDsodium arsenite results in increased expression of ID3 mRNAPMID:12760830 PMID:16966095 PMID:34032870
ID3multiple interactionsEXP 6480464CTD[sodium arsenite results in increased abundance of arsenite] which results in increased expression of ID3 mRNAPMID:32076005
ID3affects bindingISOId3 (Mus musculus)6480464CTDsodium arsenite binds to ID3 proteinPMID:23523789
ID3affects localizationISOId3 (Mus musculus)6480464CTDsodium arsenite affects the localization of ID3 proteinPMID:23523789
ID3decreases expressionISOId3 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of ID3 mRNA; sodium arsenite results in decreased expression of ID3 proteinPMID:16014739 PMID:29044176
ID3increases expressionISOId3 (Mus musculus)6480464CTDsodium arsenite results in increased expression of ID3 mRNAPMID:34968464
ID3multiple interactionsISOId3 (Mus musculus)6480464CTD[sodium arsenite binds to ID3 protein] promotes the reaction [XPO1 protein affects the localization of ID3 protein]; [sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; ID3 protein inhibits the reaction [sodium arsenite results in increased expression of EGR1 mRNA]; leptomycin B inhibits the reaction [sodium arsenite affects the localization of ID3 protein]; Palmitic Acid inhibits the reaction [sodium arsenite results in increased expression of ID3 mRNA]; sodium arsenite inhibits the reaction [Palmitic Acid results in decreased expression of ID3 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA]PMID:23523789 PMID:34968464
Go Back to source page   Continue to Ontology report