GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TH | decreases expression | ISO | Th (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of TH mRNA | PMID:19121333 PMID:23283970 PMID:37682722 | TH | decreases expression | ISO | Th (Rattus norvegicus) | 6480464 | CTD | sodium arsenite results in decreased expression of TH protein | PMID:19631675 PMID:27966075 PMID:30051311 | TH | increases expression | ISO | Th (Mus musculus) | 6480464 | CTD | sodium arsenite results in increased expression of TH protein | PMID:27413109 | TH | increases expression | ISO | Th (Rattus norvegicus) | 6480464 | CTD | sodium arsenite results in increased expression of TH protein | PMID:25179238 | TH | multiple interactions | ISO | Th (Mus musculus) | 6480464 | CTD | [sodium arsenite affects the localization of NR4A2 protein] inhibits the reaction [NR4A2 protein results in increased expression of TH mRNA] | PMID:23283970 | TH | multiple interactions | ISO | Th (Rattus norvegicus) | 6480464 | CTD | Curcumin inhibits the reaction [sodium arsenite results in decreased expression of TH protein]; SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of TH protein]; sodium arsenite results in increased phosphorylation of and results in increased activity of TH protein | PMID:19631675 PMID:27966075 PMID:9288946 | | ||||||||||||||||||||||
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