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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733315
Species: Mus musculus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2multiple interactionsEXP 6480464CTDsodium arsenite inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IL2 mRNA]; sodium arsenite inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased secretion of IL2 protein]PMID:17009048
Il2affects expressionISOIL2 (Homo sapiens)6480464CTDsodium arsenite affects the expression of IL2 mRNAPMID:21776218
Il2increases expressionISOIL2 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of IL2 mRNAPMID:12760830 PMID:21281968
Il2multiple interactionsISOIL2 (Homo sapiens)6480464CTDsodium arsenite affects the reaction [Plant Extracts results in increased expression of IL2 mRNA]; sodium arsenite inhibits the reaction [Plant Extracts results in increased secretion of IL2 protein]; sodium arsenite results in decreased expression of and results in decreased secretion of IL2 proteinPMID:12757736 PMID:21281968
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