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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733158
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfb3
Name: transforming growth factor, beta 3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb3decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of TGFB3 mRNAPMID:16014739
Tgfb3increases expressionISOTgfb3 (Rattus norvegicus)6480464CTDsodium arsenite results in increased expression of TGFB3 mRNAPMID:11241755
Tgfb3increases expressionISOTGFB3 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of TGFB3 mRNAPMID:12016162 PMID:34032870
Tgfb3multiple interactionsISOTGFB3 (Homo sapiens)6480464CTD[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of and results in increased secretion of TGFB3 protein; [Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFB3 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFB3 mRNA]PMID:29408318
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