GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ALOX5 | decreases expression | EXP | | 6480464 | CTD | sodium arsenite results in decreased expression of ALOX5 mRNA | PMID:34032870 | ALOX5 | multiple interactions | EXP | | 6480464 | CTD | [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein; SB 203580 inhibits the reaction [sodium arsenite results in increased activity of ALOX5 protein]; SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of ALOX5 protein]; sodium arsenite results in increased phosphorylation of and results in increased activity of ALOX5 protein | PMID:10779545 | ALOX5 | decreases expression | ISO | Alox5 (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of ALOX5 mRNA | PMID:37682722 | ALOX5 | increases expression | ISO | Alox5 (Mus musculus) | 6480464 | CTD | sodium arsenite results in increased expression of ALOX5 mRNA | PMID:25065748 | |
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