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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732644
Species: Homo sapiens
RGD Object: Gene
Symbol: ATP1A3
Name: ATPase Na+/K+ transporting subunit alpha 3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATP1A3affects methylationEXP 6480464CTDsodium arsenite affects the methylation of ATP1A3 genePMID:28589171
ATP1A3decreases expressionISOAtp1a3 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of ATP1A3 mRNAPMID:37682722
ATP1A3decreases expressionISOAtp1a3 (Rattus norvegicus)6480464CTDsodium arsenite results in decreased expression of ATP1A3 mRNA; sodium arsenite results in decreased expression of ATP1A3 proteinPMID:29459688 PMID:35314868
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