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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731906
Species: Homo sapiens
RGD Object: Gene
Symbol: IL23A
Name: interleukin 23 subunit alpha
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL23Aincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of IL23A mRNAPMID:34032870
IL23Aaffects expressionISOIl23a (Mus musculus)6480464CTDsodium arsenite affects the expression of IL23A mRNAPMID:28843991
IL23Amultiple interactionsISOIl23a (Mus musculus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA]; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL23A protein]; [sodium arsenite results in increased abundance of Arsenic] which affects the expression of IL23A mRNA; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL23A protein]]PMID:30889423 PMID:33049506
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