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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708512
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc1a5
Name: solute carrier family 1 member 5
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a5increases expressionISOSLC1A5 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of SLC1A5 mRNA; sodium arsenite results in increased expression of SLC1A5 proteinPMID:33781819
Slc1a5increases expressionISOSlc1a5 (Mus musculus)6480464CTDsodium arsenite results in increased expression of SLC1A5 mRNAPMID:31170414
Slc1a5multiple interactionsISOSLC1A5 (Homo sapiens)6480464CTDdimethyl alpha-ketoglutarate inhibits the reaction [SLC1A5 protein affects the reaction [sodium arsenite results in increased phosphorylation of EIF4EBP1 protein]]; dimethyl alpha-ketoglutarate inhibits the reaction [SLC1A5 protein affects the reaction [sodium arsenite results in increased phosphorylation of RPS6KB1 protein]]; SLC1A5 protein affects the reaction [sodium arsenite results in increased expression of CCND1 protein]; SLC1A5 protein affects the reaction [sodium arsenite results in increased expression of PCNA protein]; SLC1A5 protein affects the reaction [sodium arsenite results in increased phosphorylation of EIF4EBP1 protein]; SLC1A5 protein affects the reaction [sodium arsenite results in increased phosphorylation of RPS6KB1 protein]PMID:33781819
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