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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Irs2
Name: insulin receptor substrate 2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7362056480464CTDsodium arsenite results in decreased expression of IRS2 mRNA, sodium arsenite results in decreased expression of IRS2 protein

PMID:22285432
multiple interactionsISORGD:7362056480464CTDgingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS2 mRNA], gingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS2 protein]

PMID:22285432
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