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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69273
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Socs2
Name: suppressor of cytokine signaling 2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Socs2affects methylationISOSOCS2 (Homo sapiens)6480464CTDsodium arsenite affects the methylation of SOCS2 genePMID:28589171
Socs2decreases expressionISOSocs2 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of SOCS2 mRNAPMID:28283972
Socs2decreases expressionISOSOCS2 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of SOCS2 mRNAPMID:25493608
Socs2increases expressionISOSOCS2 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of SOCS2 mRNAPMID:21281968 PMID:34032870
Socs2multiple interactionsISOSocs2 (Mus musculus)6480464CTD[Dietary Fats co-treated with sodium arsenite] results in decreased expression of SOCS2 mRNAPMID:28283972
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