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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69218
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of ALDH2 mRNA

PMID:18812580
increases expressionEXP 6480464CTDsodium arsenite results in increased expression of ALDH2 protein

PMID:29044176
increases expressionISORGD:692206480464CTDsodium arsenite results in increased expression of ALDH2 mRNA

PMID:20886546, PMID:23876855
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.