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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68978
Species: Homo sapiens
RGD Object: Gene
Symbol: CLU
Name: clusterin
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CLUdecreases activityEXP 6480464CTDsodium arsenite results in decreased activity of CLU proteinPMID:30528433
CLUdecreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of CLU mRNAPMID:34032870
CLUincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of CLU mRNAPMID:12377979 PMID:12760830 PMID:20886546
CLUmultiple interactionsEXP 6480464CTDsodium arsenite inhibits the reaction [CLU protein binds to Ribonucleotides]PMID:30528433
CLUdecreases expressionISOClu (Mus musculus)6480464CTDsodium arsenite results in decreased expression of CLU mRNAPMID:37682722
CLUmultiple interactionsISOClu (Mus musculus)6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of CLU mRNAPMID:34876320
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