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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a2
Name: collagen type I alpha 2 chain
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7309856480464CTDsodium arsenite results in decreased expression of COL1A2 mRNA

PMID:18812580
increases expressionISORGD:7309846480464CTDsodium arsenite results in increased expression of COL1A2 mRNA

PMID:18182400
increases expressionISORGD:7309856480464CTDsodium arsenite results in increased expression of COL1A2 mRNA

PMID:19095001, PMID:28370166
multiple interactionsISORGD:7309846480464CTDEthanol inhibits the reaction [sodium arsenite results in increased expression of COL1A2 mRNA]

PMID:18182400
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.