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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plin1
Name: perilipin 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plin1affects expressionISOPLIN1 (Homo sapiens)6480464CTDsodium arsenite affects the expression of PLIN1 proteinPMID:27932253
Plin1decreases expressionISOPLIN1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of PLIN1 mRNA; sodium arsenite results in decreased expression of PLIN1 proteinPMID:23650128 PMID:29301061 PMID:37956786
Plin1decreases expressionISOPlin1 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of PLIN1 proteinPMID:23650128
Plin1increases expressionISOPlin1 (Mus musculus)6480464CTDsodium arsenite results in increased expression of PLIN1 mRNAPMID:31170414
Plin1multiple interactionsISOPLIN1 (Homo sapiens)6480464CTDBQ 610 inhibits the reaction [sodium arsenite results in decreased expression of PLIN1 protein]; EDNRA protein affects the reaction [sodium arsenite results in decreased expression of PLIN1 protein]; Pertussis Toxin inhibits the reaction [sodium arsenite results in decreased expression of PLIN1 mRNA]; Pertussis Toxin inhibits the reaction [sodium arsenite results in decreased expression of PLIN1 protein]PMID:23650128
Plin1multiple interactionsISOPlin1 (Mus musculus)6480464CTD[Dietary Fats co-treated with sodium arsenite] results in decreased phosphorylation of PLIN1 proteinPMID:36801214
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