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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2553
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eno1
Name: enolase 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eno1increases expressionEXP 6480464CTDsodium arsenite results in increased expression of ENO1 proteinPMID:16456883 PMID:29459688
Eno1multiple interactionsEXP 6480464CTDBenzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of ENO1 protein]; sodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of ENO1 protein]PMID:16456883
Eno1decreases expressionISOENO1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of ENO1 proteinPMID:20050688
Eno1increases expressionISOEno1 (Mus musculus)6480464CTDsodium arsenite results in increased expression of ENO1 mRNAPMID:17450228
Eno1increases expressionISOENO1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of ENO1 mRNA; sodium arsenite results in increased expression of ENO1 proteinPMID:23648393 PMID:27287256 PMID:34032870
Eno1multiple interactionsISOENO1 (Homo sapiens)6480464CTDHIF1A protein affects the reaction [sodium arsenite results in increased expression of ENO1 protein]; HIF1A protein inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of ENO1 protein]]; MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of ENO1 protein]; sodium arsenite results in increased expression of and results in increased secretion of ENO1 proteinPMID:26259607 PMID:27287256
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