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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593163
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sprr1a
Name: small proline-rich protein 1A
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sprr1adecreases expressionISOSPRR1A (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of SPRR1A mRNA; sodium arsenite results in decreased expression of SPRR1A proteinPMID:11485391 PMID:28713220
Sprr1adecreases expressionISOSprr1a (Mus musculus)6480464CTDsodium arsenite results in decreased expression of SPRR1A mRNAPMID:37682722
Sprr1aincreases expressionISOSPRR1A (Homo sapiens)6480464CTDsodium arsenite results in increased expression of SPRR1A mRNAPMID:34032870
Sprr1amultiple interactionsISOSprr1a (Mus musculus)6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of SPRR1A mRNAPMID:34876320
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