GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDK2 | increases expression | EXP | | 6480464 | CTD | sodium arsenite results in increased expression of CDK2 mRNA; sodium arsenite results in increased expression of CDK2 protein | PMID:28595984 PMID:29301061 PMID:33261869 PMID:34032870 | CDK2 | multiple interactions | EXP | | 6480464 | CTD | NFE2L2 protein affects the reaction [sodium arsenite results in increased expression of CDK2 protein]; NQO1 protein affects the reaction [sodium arsenite results in increased expression of CDK2 protein]; sodium arsenite inhibits the reaction [Estradiol results in decreased phosphorylation of CDK2 protein]; sodium arsenite results in decreased expression of and results in decreased activity of CDK2 protein; sodium arsenite results in increased phosphorylation of and results in increased activity of CDK2 protein | PMID:17545210 PMID:28880708 PMID:29039521 PMID:33261869 | CDK2 | decreases activity | ISO | Cdk2 (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased activity of CDK2 protein | PMID:11807808 | CDK2 | decreases expression | ISO | Cdk2 (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of CDK2 protein | PMID:20336670 | CDK2 | multiple interactions | ISO | Cdk2 (Mus musculus) | 6480464 | CTD | SB 203580 inhibits the reaction [sodium arsenite results in decreased activity of CDK2 protein]; sodium arsenite promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] | PMID:11807808 | | ||||||||||||||||||||||
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