Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3increases expressionEXP 6480464CTDsodium arsenite results in increased expression of NLRP3 proteinPMID:34920032
Nlrp3multiple interactionsEXP 6480464CTD[sodium arsenite co-treated with Lipopolysaccharides] promotes the reaction [SERPINH1 protein binds to NLRP3 protein]; [sodium arsenite co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[sodium arsenite co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]PMID:35963424
Nlrp3increases expressionISONlrp3 (Mus musculus)6480464CTDsodium arsenite results in increased expression of NLRP3 proteinPMID:33290778
Nlrp3multiple interactionsISONLRP3 (Homo sapiens)6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]PMID:32645460
Nlrp3multiple interactionsISONlrp3 (Mus musculus)6480464CTDSEMA4A protein promotes the reaction [sodium arsenite results in increased expression of NLRP3 protein]PMID:33290778
Go Back to source page   Continue to Ontology report