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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10869
Species: Mus musculus
RGD Object: Gene
Symbol: Lhb
Name: luteinizing hormone beta
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lhbdecreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of LHB proteinPMID:32991915 PMID:33242462
Lhbmultiple interactionsEXP 6480464CTDChlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]PMID:33242462
Lhbdecreases expressionISOLhb (Rattus norvegicus)6480464CTDsodium arsenite results in decreased expression of LHB proteinPMID:12883085 PMID:16483355 PMID:20146381 PMID:20580664 PMID:20598115 PMID:21964460 PMID:31163222 PMID:31199764
Lhbdecreases secretionISOLhb (Rattus norvegicus)6480464CTDsodium arsenite results in decreased secretion of LHB proteinPMID:27151894
Lhbmultiple interactionsISOLhb (Rattus norvegicus)6480464CTDCurcumin inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]; Glutathione inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]; Polysaccharides inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]; Sodium Selenite inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]; Succimer inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]; Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]PMID:12883085 PMID:20580664 PMID:21964460 PMID:31163222 PMID:31199764
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