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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10390
Species: Mus musculus
RGD Object: Gene
Symbol: Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cpt1adecreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of CPT1A mRNAPMID:31532247
Cpt1aincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of CPT1A mRNAPMID:26151952
Cpt1amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with sodium arsenite] results in increased expression of CPT1A mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CPT1A mRNAPMID:30208560 PMID:32045263
Cpt1aaffects methylationISOCPT1A (Homo sapiens)6480464CTDsodium arsenite affects the methylation of CPT1A genePMID:28589171
Cpt1adecreases expressionISOCPT1A (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of CPT1A mRNA; sodium arsenite results in decreased expression of CPT1A proteinPMID:30334557
Cpt1aincreases expressionISOCPT1A (Homo sapiens)6480464CTDsodium arsenite results in increased expression of CPT1A mRNAPMID:34032870
Cpt1amultiple interactionsISOCPT1A (Homo sapiens)6480464CTDEPAS1 protein affects the reaction [sodium arsenite results in decreased expression of CPT1A protein]PMID:30334557
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