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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62088
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2ry2
Name: purinergic receptor P2Y2
Acc ID: CHEBI:29639
Term: N-(3-oxododecanoyl)homoserine lactone
Definition: A N-acyl homoserine lactone that is the monocarboxylic acid amide arising from formal condensation of homoserine lactone with 3-oxododecanoic acid.
Chemical ID: MESH:C109860
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13524866480464CTDN-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY2 mRNA

PMID:10496880
multiple interactionsISORGD:13524866480464CTDIbuprofen inhibits the reaction [N-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY2 mRNA]

PMID:10496880
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.