GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ESR1 | affects binding | EXP | | 6480464 | CTD | azadirachtin binds to ESR1 protein | PMID:31225646 | ESR1 | increases expression | ISO | Esr1 (Mus musculus) | 6480464 | CTD | azadirachtin results in increased expression of ESR1 mRNA; azadirachtin results in increased expression of ESR1 protein | PMID:31225646 | ESR1 | multiple interactions | ISO | Esr1 (Mus musculus) | 6480464 | CTD | 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [azadirachtin results in increased expression of ESR1 mRNA]; 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [azadirachtin results in increased expression of ESR1 protein]; azadirachtin inhibits the reaction [Estrogens deficiency results in decreased expression of ESR1 mRNA]; ESR1 protein promotes the reaction [azadirachtin results in increased expression of RUNX2 mRNA]; ESR1 protein promotes the reaction [azadirachtin results in increased expression of RUNX2 protein] | PMID:31225646 | | ||||||||||||||||||||||
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