GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NOS2 | affects response to substance | ISO | Nos2 (Mus musculus) | 6480464 | CTD | NOS2 affects the susceptibility to Phosgene | PMID:25870319 | NOS2 | increases expression | ISO | Nos2 (Mus musculus) | 6480464 | CTD | Phosgene results in increased expression of NOS2 mRNA; Phosgene results in increased expression of NOS2 protein | PMID:21818760 PMID:25870319 | NOS2 | increases expression | ISO | Nos2 (Rattus norvegicus) | 6480464 | CTD | Phosgene results in increased expression of NOS2 protein | PMID:21818760 | NOS2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of NOS2 protein] | PMID:21818760 | NOS2 | multiple interactions | ISO | Nos2 (Rattus norvegicus) | 6480464 | CTD | ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein] | PMID:21818760 | | ||||||||||||||||||||||
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