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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3242
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2ry1
Name: purinergic receptor P2Y1
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2ry1multiple interactionsEXP 6480464CTD[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]PMID:16973929
P2ry1multiple interactionsISOP2RY1 (Homo sapiens)6480464CTD[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]PMID:12694404 PMID:16236484
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