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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2906
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcr2
Name: C-X-C motif chemokine receptor 2
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcr2affects transportISOCXCR2 (Homo sapiens)6480464CTDCXCR2 protein affects the transport of CalciumPMID:15618463
Cxcr2multiple interactionsISOCXCR2 (Homo sapiens)6480464CTD[CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of CalciumPMID:11298490 PMID:25833952
Cxcr2multiple interactionsISOCxcr2 (Mus musculus)6480464CTDExcitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium]PMID:15914698
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