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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69123
Species: Homo sapiens
RGD Object: Gene
Symbol: LEP
Name: leptin
Acc ID: CHEBI:2930
Term: Aurothioglucose
Definition: An oxane that has formula C6H11AuO5S.
Chemical ID: MESH:D006051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LEPincreases expressionISOLep (Mus musculus)6480464CTDAurothioglucose results in increased expression of LEP mRNA; Aurothioglucose results in increased expression of LEP proteinPMID:15809509 PMID:7489415 PMID:9794456
LEPmultiple interactionsISOLep (Mus musculus)6480464CTD[Sodium Glutamate co-treated with Aurothioglucose] results in increased expression of LEP mRNA; [Sodium Glutamate co-treated with Aurothioglucose] results in increased expression of LEP proteinPMID:9794456
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