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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734431
Species: Homo sapiens
RGD Object: Gene
Symbol: NFE2L2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:29132
Term: N-acetyl-1,4-benzoquinone imine
Definition: A ketoimine that has formula C8H7NO2.
Chemical ID: MESH:C028473
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFE2L2affects localizationISONfe2l2 (Mus musculus)6480464CTDN-acetyl-4-benzoquinoneimine affects the localization of NFE2L2 proteinPMID:18785192
NFE2L2increases activityISONfe2l2 (Mus musculus)6480464CTDN-acetyl-4-benzoquinoneimine results in increased activity of NFE2L2 proteinPMID:18785192
NFE2L2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein affects the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]PMID:18785192 PMID:19246624
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