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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61957
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Isl1
Name: ISL LIM homeobox 1
Acc ID: CHEBI:29073
Term: L-ascorbic acid
Definition: The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.
Chemical ID: MESH:D001205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Isl1increases expressionISOIsl1 (Mus musculus)6480464CTDAscorbic Acid results in increased expression of ISL1 mRNAPMID:15305145
Isl1multiple interactionsISOISL1 (Homo sapiens)6480464CTD[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNAPMID:34480604
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