GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl15 | affects expression | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid affects the expression of CXCL8 mRNA; Ascorbic Acid deficiency affects the expression of CXCL8 mRNA | PMID:19932582 | Cxcl15 | multiple interactions | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Ascorbic Acid affects the reaction [Homocysteine results in increased secretion of CXCL8 protein]; Ascorbic Acid affects the reaction [homocysteine thiolactone results in increased secretion of CXCL8 protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] | PMID:16715183 PMID:25551565 PMID:26270818 | |
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