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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mpo
Name: myeloperoxidase
Acc ID: CHEBI:29073
Term: L-ascorbic acid
Definition: The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.
Chemical ID: MESH:D001205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpomultiple interactionsEXP 6480464CTD[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein]; Ascorbic Acid inhibits the reaction [Fluorouracil results in increased activity of MPO protein]; Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of MPO protein]PMID:18726076 PMID:26921358 PMID:27020608 PMID:31022331
Mpomultiple interactionsISOMPO (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]PMID:19462961
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