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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562979
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ikzf1
Name: IKAROS family zinc finger 1
Acc ID: CHEBI:29073
Term: L-ascorbic acid
Definition: The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.
Chemical ID: MESH:D001205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikzf1decreases activityISOIKZF1 (Homo sapiens)6480464CTDAscorbic Acid results in decreased activity of IKZF1 proteinPMID:17664058
Ikzf1multiple interactionsISOIKZF1 (Homo sapiens)6480464CTD2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]; 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]PMID:17664058
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