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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2503
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:29028
Term: glucobrassicin
Definition: An indolylmethylglucosinolic acid that is 1-thio-beta-D-glucopyranose having a 2-(1H-indol-3-yl)-N-(sulfooxy)ethanimidoyl group attached to the anomeric sulfur.
Chemical ID: MESH:C048308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1decreases activityISONQO1 (Homo sapiens)6480464CTDglucobrassicin analog results in decreased activity of NQO1 proteinPMID:20868228
Nqo1multiple interactionsISONQO1 (Homo sapiens)6480464CTDglucobrassicin analog inhibits the reaction [glucoraphanin results in increased activity of NQO1 protein]PMID:20868228
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