Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1354178
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	DNMT1
Name:	DNA methyltransferase 1

Acc ID:	CHEBI:29021
Term:	hexane
Definition:	An unbranched alkane containing six carbon atoms.
Chemical ID:	MESH:C026385

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
DNMT1	decreases methylation	ISO	Dnmt1 (Rattus norvegicus)	6480464	CTD	n-hexane results in decreased methylation of DNMT1 promoter	PMID:23740543

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.