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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552578
Species: Mus musculus
RGD Object: Gene
Symbol: Chrm2
Name: cholinergic receptor, muscarinic 2, cardiac
Acc ID: CHEBI:28973
Term: strychnine
Definition: A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
Chemical ID: MESH:D013331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrm2affects bindingISOCHRM2 (Homo sapiens)6480464CTDStrychnine binds to CHRM2 proteinPMID:15647330
Chrm2multiple interactionsISOCHRM2 (Homo sapiens)6480464CTDStrychnine promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]PMID:9495826
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