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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735631
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP11A1
Name: cytochrome P450 family 11 subfamily A member 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:693256480464CTDAcetylcysteine inhibits the reaction [Dimethoate results in decreased expression of CYP11A1 mRNA], Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA], Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]

PMID:26769589, PMID:29567110
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.