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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731720
Species: Homo sapiens
RGD Object: Gene
Symbol: CCN1
Name: cellular communication network factor 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCN1increases expressionEXP 6480464CTDAcetylcysteine results in increased expression of CCN1 mRNA; Acetylcysteine results in increased expression of CCN1 proteinPMID:21055460
CCN1multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]PMID:21055460
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