GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | VEGFA | decreases expression | EXP | | 6480464 | CTD | Acetylcysteine results in decreased expression of VEGFA mRNA | PMID:18930813 | VEGFA | decreases secretion | EXP | | 6480464 | CTD | Acetylcysteine results in decreased secretion of VEGFA protein | PMID:17992120 | VEGFA | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in decreased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in decreased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein] | PMID:11214823 PMID:11641398 PMID:11886167 PMID:13679210 PMID:15788408 PMID:16309584 PMID:16757516 PMID:18829485 PMID:19176594 PMID:19622383 PMID:19910455 PMID:27856279 PMID:30878009 PMID:35430258 | VEGFA | multiple interactions | ISO | Vegfa (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] | PMID:21804221 | VEGFA | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of VEGFA protein] | PMID:20850416 | | ||||||||||||||||||||||
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