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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620416
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnm1l
Name: dynamin 1-like
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnm1lmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 affects the reaction [DNM1L protein binds to DNM1L protein binds to DNM1L protein binds to DNM1L protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of DNM1L protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of DNM1L protein]PMID:20307494 PMID:30641872 PMID:37499777
Dnm1lmultiple interactionsISODNM1L (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of and results in increased phosphorylation of DNM1L protein]PMID:37084995
Dnm1lmultiple interactionsISODnm1l (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Diethylhexyl Phthalate affects the localization of DNM1L protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the phosphorylation of DNM1L protein]PMID:31408635
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