Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]PMID:24810974
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Formaldehyde results in decreased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IFNG protein]PMID:18849615 PMID:22440610 PMID:26138014 PMID:32620109
Ifngmultiple interactionsISOIfng (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]PMID:12847270 PMID:15004186 PMID:20431929
Go Back to source page   Continue to Ontology report